who lose

[arzgol]

Is my sentence correct?

During economic crises simple workers will be expected to be the first to/ who lose their jobs.

Thank you for spending the time to answer my question.

[emsr2d2]

Is my sentence correct?

During economic crises simple workers will be expected to be the first to/ who lose their jobs.

Thank you for spending the time to answer my question.

During economic crises, low-level workers can expect to be the first to lose their jobs.

Try not to use "simple" to describe people. In BrE, it means "quite stupid" or "peasant-like".

[arzgol]

How about a layman, unskilled workers.

[emsr2d2]

How about a layman, unskilled workers.

Unskilled workers is fine. Laymen has a different connotation - either someone who is not a member of the clergy, or people who are not part of a specific profession.