to jumble up - to change around

[dilodi83]

- There were many objects changed around/ jumbled up on my desk.

- When Francisco got into my room and sat down at my desk he changed many things around/ jumbled many things up!

Do these two verbs mean the same? Can they be used in the same contexts?

[Barb_D]

You can move things around so their position is changed without making a mess.

If things are left in a jumble, he made a mess.

[dilodi83]

You can move things around so their position is changed without making a mess.

If things are left in a jumble, he made a mess.

And what about the two sentences I have written? Do they make sense? Are they possible in English?

[Barb_D]

They are possible, yes.

I'd probably say it more like this:
When Francisco used my desk, he left everything in a mess. (I don't use "Jumble")
When Francisco used my desk, he moved everything around/he didn't leave things they way he found them,