certainly vs. of course

[nyggus]

Hi. “Certainly” vs. “of course”: is there any difference in the meaning of these two phrases in formal writing?

Best,
Nyggus

[Casiopea]

What's the context?

[nyggus]

What's the context?

For instance:
1. "Of course/Certainly, this procedure may be applied only if the requirements mentioned are fulfilled."
2. This is true, of course/certainly, when one plans a survey based on high quality auxiliary information."

Thanks,
Nyggs

[Casiopea]

Try,

Of course, this procedure may be applied only if ...
This is certainly true ...