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Although she had signed a pledge of abstinence while in adolescence, Frances Willard was 35 years old before she chose to become a temperance activist.
what's wrong with the "while in adolescence" in the sentence?
It could be seen to tie abstinence and adolescence together, as the plege was a pledge to abstain during her adolescence, as opposed to adolescence being the time in her life when she signed the pledge.
in adolescence 
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