Hi Roya,
It would be unusual to use the term 'how are you? in a formal letter. It is more likely to be used in a personal way.
Also you have made quite a few spelling and grammatical errors...
Dear sir/madam,
I translate correspondence from Persian to English and I need some information about formal letters.
At the moment I have one question: do English speakers use 'how are you?' in their formal letters?
I would be grateful if you could help me with this.
yours sincerely.
roya ghasemy
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