Re: Comma usage
You don't need a comma after "Now," unless you want your reader to pause.
The one before "and" is a style choice. I just about always use the serial or Oxford comma, as it's called, to separate the next-to-last element in a list from the last. The longer the elements in the list, the more I think it's advisable. But you will be correct either way.
I'm not a teacher, but I write for a living. Please don't ask me about 2nd conditionals, but I'm a safe bet for what reads well in (American) English.