1 Are you a man, or do you have to get your girlfriend to OK everything?
2 Could mean several things:
Run until you drop.
Risk everything in order to win - even taking suicidal risks.
You are admitting defeat before you start. Going onto a court feeling that way is suicide.
And there could well be other meanings - apart from possible mis-hearing: 'Two a side'? (Two a side is a strenuous training activity. Each player has to run much more than usual.)