No one but the author can answer your first question; but Blanche Dubois has to take a streetcar named "Desire" when she is going to her sister's home.
Any interpretation is as valid as any other; I don't consider the play to be representative of any "clash" between North and South.
Blanche lives in a world she creates for herself that does not exist and possibly never existed because she can't stand reality. So she is not very stable to begin with.
For me, Stella is attracted to Kowalski because of the latter raw sexuality; and Kowalski hates Blanche because, in a way, he feels she is better than him. He doesn't understand her, and he seeks to destroy what he doesn't understand.
He crushed the budding romance between Blanche and his mate Mitch; and he utterly destroys her when he rapes her.