1623, "fit of ill humor," perhaps imitative of an exclamation of disgust (cf. Ger. muffen "to sulk"). The verb is from 1797. Miffy (adj.) "liable to 'take a miff' " is from 1810; miffed is 1824 (Sir Walter Scott calls it "a women's phrase").
a women's phrase=?
( The word of 'miff' usually applied to women?)