Student or Learner
1) Is your house located along the same direction/along the same route/on the way as the shopping mall?
2) The new station has been relocated, so the bus system has changed. (System change= different area to take the bus).
For the first one, try: "Is your house on the way to the shopping mall?" For the second one, say "The new station has been relocated, so the bus routes have changed."