Student or Learner
I read this from 29 Gifts by Cami Walker:
"In the case of Multiple sclerosis, the immune system attacks the myelin, a protective fatty layer surrounding the nerves. Think of it as insulation that keeps the nerves firing smoothly. ... I imagine little holes being eaten in my nerve linings that leave areas of raw, exposed nerve prone to misfiring."
What do "fire" and "misfre" mean in this context?
(Not a teacher)
27. to discharge (a gun).
28. to project (a bullet or the like) by or as if by discharging from a gun.
Discharge is probably a more appropriate word, but 'fire' is the word used to describe the stimulation of a nerve in the body to send it's action potential (electrical signal). Misfire is the opposite, i.e. a nerve which doesn't release it's action potential (or in the case of Multiple Sclerosis, releases the signal, but it fails to reach the nerve ending.)