The address is oddly written.
It could be that the buliding number is 220, and the apartment or office suite is E.
It could be that the building number is 220, and it's East Avenue 28.
Usually in the US, we'd say 28th Avenue on an address.
220 28th Avenue, Apartment E
220E 28th Avenue
220 E. 28th Avenue (that would be East 28th)
I can't tell with your example.
Student or Learner