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    #1

    Does "they" refer to "mice"?

    Context:

    That doesnít mean that Alzheimerís patients should be asking their doctors for a prescription of bexarotene just yet. The mouse model of Alzheimerís isnít perfect. Mice donít get Alzheimerís the same way humans do. They build up amyloid protein in the brain, and those deposits form plaques that disrupt nerve function and affect learning and memory, just like they do in Alzheimerís patients; but in mice, there is no progressive worsening of the condition resulting in the destruction of nerve fibers. Humans lose brain cells and suffer the buildup of detritus from a dying neural network.

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    #2

    Re: Does "they" refer to "mice"?

    Quote Originally Posted by 5jj View Post
    They build up amyloid protein in the brain, and those deposits form plaques that disrupt nerve function and affect learning and memory, just like they do in Alzheimer’s patients; but in mice, there is no progressive worsening of the condition resulting in the destruction of nerve fibers. .
    But they (do in Alzheimer’s patients) refers to mice? (that is why it causes confusing)
    Last edited by 5jj; 14-Feb-2012 at 09:12. Reason: My incorrect remarks emoved - 5jj

  1. Raymott's Avatar
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    #3

    Re: Does "they" refer to "mice"?

    Quote Originally Posted by NewHopeR View Post
    But they (do in Alzheimer’s patients) refers to mice? (that is why it causes confusing)
    I think that bolded "they" can only refer to mice.
    For one thing, if "They build up plaque ... just like Alzheimers patients do", then "they" are not Alzheimer's patients.

  2. 5jj's Avatar
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    #4

    Re: Does "they" refer to "mice"?

    Quote Originally Posted by Raymott View Post
    I think that "they" can only refer to mice.
    I will delete my last post, which is misleading.

  3. 5jj's Avatar
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    #5

    Re: Does "they" refer to "mice"?

    A fresh attempt:

    The mouse model of Alzheimerís isnít perfect. Mice donít get Alzheimerís the same way humans do. They (mice) build up amyloid protein in the brain, and those deposits form plaques that disrupt nerve function and affect learning and memory, just like they (plaques) do in Alzheimerís patients; but in mice, there is no progressive worsening of the condition resulting in the destruction of nerve fibers. Humans lose brain cells and suffer the buildup of detritus from a dying neural network.[/QUOTE]

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    #6

    Re: Does "they" refer to "mice"?

    Quote Originally Posted by 5jj View Post
    A fresh attempt:

    The mouse model of Alzheimerís isnít perfect. Mice donít get Alzheimerís the same way humans do. They (mice) build up amyloid protein in the brain, and those deposits form plaques that disrupt nerve function and affect learning and memory, just like they (plaques) do in Alzheimerís patients; but in mice, there is no progressive worsening of the condition resulting in the destruction of nerve fibers. Humans lose brain cells and suffer the buildup of detritus from a dying neural network.
    [/QUOTE]

    Such usage sounds extremly awkward.


    My attempt:

    The mouse model of Alzheimerís isnít perfect. Mice donít get Alzheimerís the same way humans do. They (mice) build up amyloid protein in the brain, and those deposits form plaques (that <in human cases - human Alzheimer's patients> disrupt nerve function and affect learning and memory; however, in mice, the plaques will not cause a progressive worsening of the condition resulting in the destruction of nerve fibers). Humans lose brain cells and suffer the buildup of detritus from a dying neural network.

  4. 5jj's Avatar
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    #7

    Re: Does "they" refer to "mice"?

    Quote Originally Posted by NewHopeR View Post
    Such usage sounds extremly awkward.
    I do apologise for having been so clumsy in my pathetic attempt to be of assistance. I'll make sure it doesn't happen again. Ever.

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    #8

    Re: Does "they" refer to "mice"?

    Quote Originally Posted by 5jj View Post
    I do apologise for having been so clumsy in my pathetic attempt to be of assistance. I'll make sure it doesn't happen again. Ever.
    I should have expressed my opinion in a better way.

    You are one of the best moderators in this forum in my view. Of course, we're all human.

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