Interested in Language
1. What's it made from?
2. What's it made of?
3. What's it made out of?
Which of the above are native speakers more likely to use? Is there any preference at all?
Any of them might be used by a native speaker.
I would tend to use "made from" when referring to something which is made up of individual components (as in "bits from an old car"), and "made of" when referring to the type of physical material (as in "made of wood"). "Made out of" would do for either. However, I would stress that these are my own personal preferences; someone else might use them entirely differenntly.
I'm not a teacher of English, but I have spoken it for (almost) all of my life....