Permanent cures have been thus effected

[Mher]

Dear friends,

Any idea what this clause could mean. "On the contrary, we not only indulged but encouragedthem; and many of our most permanent cures have been thus effected."

"Most of our best treatment methods hinged on this approach"— is this close to what Poe says?

[GoesStation]

Thus effected means "done this way", so I'd say "Many of our best treatment methods have used this approach."