for me as a student i would say " give me an answer " or " could you answer my question please ",
i'm sure that the second sentence is incorrect " Pls give an answer to my question ", coz 'to' is usually used in movments like
go to the USA, go shopping, go home,
i cant really think for an exception ...
about the first sentence, ermm, it appears for me that it's correct, but not sure 100%. hope one of the teachers could help.
tashakur adurm :)
Student or Learner