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In a radio address on Saturday, Mr Bush will say he is deeply troubled by the treatment of some military veterans in a Washington medical centre.
He is forming a cross-party commission to oversee how they have been handled.
Army Secretary Francis Harvey and the medical centre's commander resigned over the allegations.
The move follows critical reports in the US media about the care of troops wounded in Afghanistan and Iraq at Washington's Walter Reed hospital. The Washington Post said last week that some of the soldiers lived in buildings infested with rodents and cockroaches.
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