Self-destructive means doing things that might cause physical, economic or other harm to oneself.
Here's Merriam Webster's entry for co-dependent:
Main Entry: coĚdeĚpenĚdenĚcy
: a psychological condition or a relationship in which a person is controlled or manipulated by another who is affected with a pathological condition (as an addiction to alcohol or heroin)
- coĚdeĚpenĚdent /-d&nt/ noun or adjective