A growing reluctance to enter a calling that ends in destroying careers and reputations.
It is referring to some vocation, which by its practice, many lives would be affected, not just one person's career and reputation.
'calling' is a highly specific word to use, unless the writer is being scornful. I can't see how nuns or ministers could wreak such havoc. If we stretch it, neither could soldiers; and I don't think that anyone going into sleaze journalism would show any qualms or reluctance on ethical grounds.
By the end of this first quarter, the city had about 1,100 or so e-commerce websites.
The red is indicating some future time, but 'had' is past tense.
The two possibilities are:
By the end of this first quarter, the city will have about 1,100 or so e-commerce websites.
At the end of the last quarter, the city had about 1,100 or so e-commerce websites.
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