What do you mind?

[blizzy]

Can I say these?
A: What do you mind? What have you got against it?
B: Well that's one of these things I can't explain. The only thing I know for sure is that I'm dead set against it!

 

[Tarheel]

For the first one I would say:

Why do you mind?

Or:

Why do you care?

Or:

What's it to you?

The rest is fine.

 

[GoesStation]

... one of those things....