The "standard" phrase in the U.S. is '
a grain', but you'll occasionally hear it modified to larger amounts for the purpose of hyperbole.
At least in my region, where we have a lot of cattle ranching, if you REALLY don't trust the person, you might take everything he says with a
block of salt - a reference to the large
salt-lick blocks we put out for livestock. You can see from the images how much salt that really represents. :lol:
Again, that's not the standard saying, and many people wouldn't even understand the humor. At that point, you're basically insinuating he's a flat-out liar, versus just suggesting he might not be completely trustworthy or accurate.
AmE does use 'pinch' as an approximate measuring amount though, as in 'add a pinch of salt'.