Context:
Ovarian cancer is associated with high concentrations of vascular endothelial growth factor (VEGF), a protein associated with tumor growth and spread. Avastin precisely inhibits VEGF, high levels, which are associated with ascites development (excess fluid in the body cavity), disease worsening, and a poorer prognosis in ovarian cancer patients.
It's hard to say, as it's very badly written. I think the main sentence is
But I don't know enough about ovarian cancer to say whether my supposition makes sense.Avastin precisely inhibits VEGF. (High levels [of this] are associated with ascites development..., disease worsening, and a poorer prognosis in ovarian cancer patients).
b
It is a bit of a mess, but I would also interpret it as meaning high levels of VEGF.