I, you, he, she, it, we and they are the subject personal pronouns used in English. They are used to substitute the names of the people or things that perform actions. In English, we make no distinction between singular and plural forms of "you".
EG. She took the bus last night. (She substitutes the name of the person who took the bus.)
Me, you, him, her, it, us and them are the object personal pronouns used in English. They are used to substitute the names of the people or things that are affected by an action.
EG. John took it. (It substitutes the name of the thing that John took.)
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