Meaning: Break into many pieces
Example: The plate BROKE UP when he dropped it on the floor.
Meaning: Close an educational institution for the holidays
Example: Schools BREAK UP at the end of June for the summer holidays.
Meaning: Finish a relationship
Example: They had been going out for a couple of years before they BROKE UP.
Meaning: Become inaudible over the telephone because of interference
Example: You're BREAKING UP; I'll call you back in a minute and see if we get a better connection.