Meaning: Spoil or ruin
Example: They MESSED UP the discussions and the contract fell through.
Notes:
- Separable [optional] 
- International English
Meaning: Make something untidy or dirty
Example: They MESSED UP the room and left stuff all over the place.
Notes:
- Separable [optional]
- International English
Meaning: Cause mental, physical or emotional problems
Example: He took a lot of LSD and it really MESSED him UP.
Notes:
- Separable [optional]
- International English
| Other Phrasal Verbs |
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We have 7 phrasal verbs with 'MESS'
- Mess about |
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Phrasal Verb Definition |
