Meaning: Start doing something new and different
Example: After doing the same job for five years, I decided to STRIKE OUT and change careers.
Meaning: Try to hit someone
Example: When he pushed me, I STRUCK OUT.
Meaning: Start going towards a place
Example: We got up early and STRUCK OUT for our final destination.
Meaning: Cross writing out
Example: As they arrived, I STRUCK their names OUT on the list I had.
Example: I tried to get the government to support us but I STRUCK OUT.