a large number of and large numbers of

Is there a difference between large numbers of and a large number of?
Is there a difference between a large amount of and large amounts of?
Thanks

/A learner/

a large amount of ~ singular

a large amounts of ~ plural

"large numbers of" and "a large number of"could be wrong use?


In addition

Should this have been said by way

Are there any differences between a large amount of and large amounts of?

There is no difference that I can think of.