crawling out of my skin

[pojeda]

used by manic patients; what does this mean?

[Tdol]

It's not a standard phrase that I have heard, nor can I find it. If your flesh crawls, you are frightened and disgusted, so would it make sense to think along those lines?

[rogul1]

it means revulsion, disgust, often just "my skin was crawling" - i guess it comes from the sensation of having insects crawl over your skin.