[Vocabulary] Permanent cures have been thus effected

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Mher

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Dear friends,

Any idea what this clause could mean. "On the contrary, we not only indulged but encouragedthem; and many of our most permanent cures have been thus effected."

"Most of our best treatment methods hinged on this approach"— is this close to what Poe says?
 
Thus effected means "done this way", so I'd say "Many of our best treatment methods have used this approach."
 
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