a designer antibody vs. a designed antibody

[GoodTaste]

What is the difference between "a designer antibody" and "a designed antibody"? Are they interchangeable?

I searched online and found: Designer AntibodyAn antibody genetically engineered for target site specificity or for a specific purpose.
And
Engineered and designed antibodies, includes those containing variable antibody domains as antigen-binding fragments (Fab) and nanobodies (Nb), and have been increasingly attracting attention mainly due to their ease of manufacturing and tissue penetration while maintaining target specificity.

They look the same thing. I am not very sure.

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A nasal spritz of a designer antibody offers strong protection against variants of the coronavirus SARS-CoV-2 — at least in mice1.


Since the early days of the pandemic, scientists have been developing antibodies as treatments for COVID-19. Today, several such antibodies are in late-stage clinical trials, and a handful have been approved for emergency use by regulatory agencies in the United States and elsewhere.

Source: Nature

 

[jutfrank]

It looks like the passage you quote is an attempt to define what a designer antibody is. So the writer is using the phrase designed antibody precisely to explain the term: 'designer antibodies' are antibodies that are designed. That means they're the same thing by definition.

Don't ever assume that any two synonymous terms are interchangeable. There will always be a reason to use one over the other. Think about the difference in use.

 

[Charlie Bernstein]

Right. And here's the difference:

When "designer" is an adjective, it suggests something more expensive and exclusive than an ordinary version of the item. In the 1970s, clothing makers began selling so-called "designer jeans" — that is, jeans that are not for farmers or builders or campers, but for people going out to parties, dance spots, or dinner.

Since then, the use of the adjective has been extended to apply to anything that's specially created or refined for consumers who can afford luxury products. For example, a "designer drug" is a drug that is formulated at great expense either for medicinal or recreational purposes.