Cigarette smoking is the major risk factor for Picks disease. How about now? To be honest, I too do not know what picks disease is. I just wanted to know the correct preposition.
I agree with Mike. There's a technicality. 'For' implies "for developing", while 'in' tends to mean "in the progression of".
That's the way it's mostly used in medical circles.
Lack of birth control is a major risk factor for pregnancy. In pregnancy, it's not a risk factor at all.
Bacterial infections are a risk factor in HIV.
Bacterial infection are not a risk factor for HIV.
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