f non-metastatic castration-resistant prostate cancer in men

[GoodTaste]

Darolutamide, sold under the brand name Nubeqa, is an antiandrogen medication which is used in the treatment of non-metastatic castration-resistant prostate cancer in men.[6][2][3][7][8] It is specifically approved to treat non-metastatic castration-resistant prostate cancer (nmCRPC) in conjunction with surgical or medical castration.
Source: Wikipedia https://en.wikipedia.org/wiki/Darolutamide

I understand "castration-resistant" as "of the behavior of men who refuse to accept the surgery of removing their testes for the treatment of prostate cancer". Am I on the right track?

 

[5jj]

No. Chemical castration lowers the levels of certain hormones in the testicles. The testicles are not removed.

 

[GoodTaste]

Sorry. I kewn very clearly what chemical castration meant before posting the thread.
The question is what is the meaning of "castration-resistant" - I heard that chemical castration was used in legal punishment for some serious criminals (sex offenders), in that case any resistance would be in vain since the legal enforcement is forced.

 

[jutfrank]

I'm pretty sure that the adjective castration-resistant modifying cancer means that the cancer will continue to develop despite castration treatment. In other words, castration is ineffective as a treatment.

 

[5jj]

I understand "castration-resistant" as "of the behavior of men who refuse to accept the surgery of removing their testes for the treatment of prostate cancer". Am I on the right track?

Sorry. I knew very clearly what chemical castration meant before posting the thread.

You didn't express it very clearly.

 

[Tdol]

If I must have prostate cancer, I hope it's castration-resistant.

 

[5jj]

I did. It was.

 

[Tarheel]

GoodTaste, the relevant phrase is "castration-resistant prostate cancer", which you highlighted in bold print.

 

[Tdol]

I think that this was news to a number of us reading this thread, so the confusion is understandable.