... something universities appear unprepared for.

[Mahir1250]

Students need to acquaint themselves with computer tools to cope with the modern world, something universities appear unprepared for.

Is "something" grammatically ok here, or "yet" would be the best choice?

Like this : Students need to acquaint themselves with computer tools to cope with the modern world, yet universities appear unprepared to do so.

context: self made

 

[emsr2d2]

Students need to acquaint themselves with computer tools to cope with the modern world, something universities appear unprepared for.

Is "something" grammatically ok OK/okay here, or would "yet" would be the best a better choice?

Note my changes above. At the start of a sentence, you can write "Okay" or "OK". Elsewhere in a sentence, write "OK" or "okay", but "ok" is always wrong.
Note the correct word order for a question.
I'm not sure what you mean. What exactly are universities unprepared for?

I mean like this: Students need to acquaint themselves with computer tools to cope with the modern world, yet universities appear unprepared to do so.

Don't put a space before a colon.
I still don't know what you mean. What does the "so" refer to in "universities are unprepared to do so".

Context: self-made

That's not context. When we ask for context, we mean that we need to know why you're writing it, who the intended reader is etc. You're right that we need to know that you wrote the sentence yourself, rather than copying it from somewhere else, but that doesn't qualify as context.

 

[Annabel Lee]

Students need to acquaint themselves with computer tools to cope with the modern world, something universities appear unprepared for.

"Something" is ambiguous and unclear there. It could refer to "coping with the modern world" or just "the modern world."

 

[Mahir1250]

I still don't know what you mean. What does the "so" refer to in "universities are unprepared to do so".

Here, with " so" I want to say that universities are unprepared to get students acquaint with computer tools. They've no intention or any goal.

 

[Edward B]

Students need to acquaint themselves with computer tools to cope with the modern world, something universities appear unprepared for.

Is "something" grammatically ok here, or "yet" would be the best choice?

Like this : Students need to acquaint themselves with computer tools to cope with the modern world, yet universities appear unprepared to do so.

context: self made

The first version would suggest unis are poorly equipped, but the second suggests they are unwilling.

 

[emsr2d2]

Here, with "so", I want to say that universities are unprepared to get students acquainted with computer tools. They've no intention or any goal.

There are too many things for "so" to refer back to. I'd end with "something universities seem unprepared/unwilling to help them with".