With that alone you’d be going, ‘Oh my god,’”

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GoodTaste

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Such a potential nightmare virus actually appeared last year: a variant called B.1.620 that was first seen in Africa. It carried the E484K mutation, along with a number of other spike protein mutations that might increase transmissibility. “With that alone you’d be going, ‘Oh my god,’” says Emma Hodcroft, a genetics researcher at the University of Bern in Switzerland. But the number of B.1.260 cases soon declined. “It’s clearly not quite as simple as you have all these mutations and you’re the worst thing around,” Hodcroft says.


Source: Scientific American: Why Do Variants Such as Delta Become Dominant?

I understand the phrase "With that alone you’d be going, ‘Oh my god’” as "that alone is sufficient to make you suffer and struggle." Am I on the right track?
 
You are.

More exactly, it means that it would be enough to shock you.

I would write it: "Oh, my God."
 
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